Engineering polypeptide folding through trans double bonds: transformation of miniature β-meanders to hybrid helices.

نویسندگان

  • Mothukuri Ganesh Kumar
  • Sushil N Benke
  • K Muruga Poopathi Raja
  • Hosahudya N Gopi
چکیده

Utilization of conjugated double bonds to engineer the novel folded miniature β-meander type structures, single step transformation of miniature β-meanders into ααγ(4)-hybrid peptide 10/12-helices using catalytic hydrogenation, their solution and single crystal conformations are reported.

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عنوان ژورنال:
  • Chemical communications

دوره 51 69  شماره 

صفحات  -

تاریخ انتشار 2015